Iran

Civilians and civilian infrastructure in Iran continue to bear the brunt of attacks by the United States and Israel. The Iranian Ministry of Health reports more than 1,900 deaths and nearly 25,000 injuries, including over 1,600 children and at least 4,000 women, since February 28. Casualties have been reported in at least 20 provinces, with the highest numbers in the capital, Tehran, and the province of Hormozgan.

With the humanitarian situation in Lebanon worsening by the day, health authorities report that at least 1,116 people have been killed and over 3,000 injured in Israeli attacks since March 2. Meanwhile, displacement continues to surge, with over 1.2 million people in Lebanon – around a fifth of the population – having been forced to flee their homes.

The United Nations World Food Programme (WFP) is warning that the United States' and Israel's war on Iran and the regional spillover across the Middle East could push global hunger to record levels. The ongoing conflict could cause the greatest disruption to lifesaving humanitarian work since the start of the COVID-19 pandemic and Russia's full-scale invasion of Ukraine in 2022, WFP said on Tuesday.

Humanitarian organizations are deeply concerned about the rising number of civilian casualties, including women and children, the large-scale displacement, and the increasing humanitarian needs resulting from the ongoing Israeli attacks on Lebanon. UN officials and aid agencies continue to call on all parties to protect civilians, civilian infrastructure, humanitarian personnel, and health workers.

More than four million people have been displaced as the United States and Israel continue to wage war against Iran, triggering a rapidly worsening humanitarian crisis across the Middle East. Aid agencies warn that the conflict has already caused thousands of civilian deaths and injuries, as well as the widespread destruction of homes and infrastructure, and growing shortages of essential services.

At a time of severe cuts to the global body’s humanitarian work in emergencies and “soaring” needs, the UN’s relief chief has condemned the “$1 billion-a-day” cost of the war roiling Iran and the wider Middle East. On Wednesday in Geneva, he spoke about his efforts to reach 87 million people with life-saving aid, for which US$23 billion is urgently needed.

Military strikes and counter-strikes continue across the Middle East region as the United States and Israel wage war on Iran causing thousands of civilian deaths and injuries. On Friday, UN chief António Guterres warned that "the situation could spiral beyond anyone’s control. " Meanwhile, Tom Fletcher, the UN relief chief, described the current state of affairs as one of "grave peril," appealing for urgent protection of civilians.

Intense Israeli airstrikes across Lebanon have caused widespread displacement and a rising death toll, following the escalation of hostilities sparked by the U.S.-Israeli initiation of war against Iran. The attacks, which began Monday, have displaced tens of thousands and raised urgent humanitarian concerns throughout the country.

Hundreds of civilians have been reportedly killed following large-scale United States and Israeli missile and air strikes across Iran, according to Iranian state media and humanitarian sources. On Saturday evening, Iran’s Red Crescent reported to state media that more than 200 civilians were killed and more than 700 were injured during the first day of strikes across 24 of Iran’s 31 provinces.

Amid the ongoing humanitarian and human rights crisis in Afghanistan, United Nations agencies and non-governmental organizations (NGOs) are urgently calling for international support as the country faces one of the largest return movements in recent history. According to the latest UN figures, more than 2.2 million Afghans returned or were forced to return from Iran and Pakistan in 2025 alone. Over 1.8 million came from Iran and nearly 400,000 arrived from Pakistan.

Sources in Iran report steadily rising numbers of fatalities from Israeli attacks. More than 450 people have reportedly been killed in the country, including dozens of women and children, and more than 1,400 people have reportedly been injured in Israeli airstrikes and missile attacks that began early Friday. Meanwhile, Israeli health authorities say that 24 people have been killed and more than 600 injured by Iranian counter-strikes since Friday.